Use of Umbilical Cord Blood for the next Generation Myocardial Tissue Regeneration
نویسندگان
چکیده
Cord blood stem cell based repair or regeneration of organs like heart, brain, liver etc. is under high priority research worldwide. Cord blood stem cells are being tried for the cure of hematological, oncological or other acute diseases. In the next generation, there is immense possibility of using cord blood stem cells (CBSCs) for myocardial regeneration. Cord blood (CB) stem cells have a high rate of engraftment, more tolerant of HLA mismatches, result in a reduced rate of graft-versus-host disease (GVHD), rarely contaminated with latent viruses and finally it is also easy to procure and restore. Results of several successful clinical trials with animal models indicate that CBSCs are even superior to the bone marrow or other sources derived stem cells for the usage in regenerative medicines. In the present review we have focused the present status and the future of CBSC research particularly in myocardial repair and regeneration.
منابع مشابه
Cord Blood
Stem cells are naïve or master cells. This means they can transform into special 200 cell types as needed by body, and each of these cells has just one function. Stem cells are found in many parts of the human body, although some sources have richer concentrations than others. Some excellent sources of stem cells, such as bone marrow, peripheral blood, cord blood, other tissue stem cells and ...
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